The dengue virus structure has sets of three, nearly parallel dimers. This animation zooms into a 3D model of dengue virus, moving from the virus’s outer structures to its inner core. Schematic diagram of the dengue virus genome and polyprotein. The virus that causes dengue is transmitted by mosquitoes. Atomic structures of individual pieces are fit into the image to form the final model. Without treatment, the virus can cause damage to blood and lymph vessels and lead to dengue hemorrhagic fever, which is marked by difficulty breathing, bruising and bleeding from the nose, gums or under the skin. Forty percent of the world’s population, about 3 billion people, live in areas with a risk of dengue. The structural proteins (open boxes) are encoded at the 5′ one third of genome followed by the non-structural … Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. As shown in the animation, the outside of the dengue virus is made up of glycoproteins arranged in geometric patterns of two-, three-, and five-fold symmetry. In the old days, solving a virus structure was a big deal. The dengue virus consists of a single-stranded positive sense RNA sequence. Dengue (of knokkelkoorts) is een infectieziekte die wordt veroorzaakt door een virus.
The dengue virus (DENV) is a flavivirus that causes the deadly disease dengue fever. Dengue is common in more than 100 countries around the world. The dengue virus is transmitted to humans through the bites of infected mosquitoes and is most often found in tropical and sub-tropical regions of the world. Dengue hemorrhagic fever is a potentially lethal complication that can cause internal bleeding, vomiting, severe abdominal pain and death. Other examples include yellow fever virus and West Nile virus. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function.
A virus is, after all, a very large assembly of many proteins. Het virus komt voor in (sub)tropische gebieden en wordt overgedragen door muggen. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. These sets associate to form a “herringbone” configuration on the viral surface. (source: Frontiers in Dengue Virus Research) Genome structure Nevertheless, scientists' understanding of dengue virus may be simplistic, as rather than distinct antigenic groups, a continuum appears to exist. aegypti or Ae. Dengue (DENV) and Zika (ZIKV) viruses are clinically important members of the Flaviviridae family with an 11 kb positive strand RNA genome that folds to enable virus function. Six months after Zika virus became a household word, we now know the three-dimensional structure of the virus particle.
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